There are NO ALLERGIC REACTIONS. these stem cells do not express specific HLAs which help them avoid the immune system. In fact, mesenchymal stem cells (MSCs) do this so well that they are in clinical studies for graft vs host disease and have been approved for pediatric graft vs host disease in Canada. These studies and data support the notion that the cells are safe to use as an “off the shelf” product such as ONESTEMCELLSHOT products.
Participating hospitals invite mothers expecting normal, healthy births to donate the resulting umbilical cord tissues. They are SCREENED FOR TRANSMITTABLE DISEASES. These otherwise discarded tissues are an excellent source of high-quality stem cells and growth factors which may be used in regenerative medicine. The umbilical cord tissue and blood is extracted and taken to our lab which follows cGMP /GTP procedures. From here our product is made.
All the tissues obtained are screened under AATB standards in order to assure the highest quality product.
STEM CELLS are unspecialized cells in our bodies that have the capacity to change into any healthy cell in our body. Stem cells are located throughout our body in almost every organ and tissue such as bone marrow, fat, teeth, muscles, etc. However, as other cells in our body, stem cells also age as we do. UMBILICAL CORD stem cells from umbilical cord tissue are young and healthy.
They have the ability to change into other cells and continue making other PROGENITOR stem cells. These cells, also known as mesenchyamal stem cells (MSC) are the most potent and have the most anti inflammatory properties.
SOURCES OF STEM CELLS:
Embryonic tissue: Most embryonic stem cells (human embryonic stem cells, or hESCs) are derived from embryos donated from fertility clinics. For the most part these cells are only used in research.
Bone marrow: Adult stem cells can be extracted from bone marrow by aspiration, This procedure may be painful, and does not yield a high concentration of stem cells. Bone marrow aspiration generates a small volume and low concentration of stem cells.
Adipose tissue: Adipose-derived stem cells come from a patient’s fat tissue, which is surgically extracted via liposuction under general anesthesia. Similarly, this procedure may also be painful, generates a small volume and low concentration of stem cells.
STEM CELLS work by migrating to injured tissues, a phenomenon called homing. This occurs by injury/disease signals that are released from the distressed cells/tissue. Once stem cells are delivered to a site of injury they go to these distress signals and dock on adjacent cells where they serve as a cell replacement. They CHANGE into the needed cell type such as a muscle cell. This is ideal for traumatic injuries and orthopedic indications.
They dock on an adjacent cell and release proteins called growth factors, cytokines and chemokines. These factors help control many aspects systemically.
i. Control the immune system and regulate inflammation which is a key mediator of diseases of aging and autoimmune diseases such as rheumatoid arthritis and multiple sclerosis.
ii. Help to increase new blood vessel formation which aids in adding vasculature so that tissues can receive proper blood flow and the correct nutrients needed to heal such is the case in stroke, peripheral artery disease and heart disease.
iii. Provide trophic support for surrounding tissues and help host endogenous repair. This works great when used for orthopedics as it causes signals to be released which may now activate your own stem cells to repair a knee for instance.